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Glycoscience and Microbial Adhesion

Published by Springer-Verlag Gmbh Jun 2009, 2009
ISBN 10: 3642013031 / ISBN 13: 9783642013034
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Title: Glycoscience and Microbial Adhesion

Publisher: Springer-Verlag Gmbh Jun 2009

Publication Date: 2009

Binding: Buch

Book Condition: Neu


Neuware - bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, Bitter sweetness of complexity, the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on (1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its guest, as well as the biological consequences resulting from this mutual interplay. 186 pp. Englisch. Bookseller Inventory # 9783642013034

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Synopsis: PMumtaz Virji: Ins and Outs of Microbial Adhesion.- Martina Lahmann: Architectures of Multivalent Glycomimetics for Probing Carbohydrate-Lectin Interactions.- Stefan D. Knight and Julie Bouckaert: Structure, Function, and Assembly of Type 1 Fimbriae.- Knut Ohlsen, Tobias A. Oelschlaeger, Jrg Hacker, A. Salam Khan: Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections.- Susann Teneberg: The Multiple Carbohydrate Binding Specificities of EMHelicobacter pylori/EM.- Andrea Kristina Horst and Christoph Wagener: Bitter Sweetness of Complexity.- Dietrich Mack, Angharad P. Davies, Llinos G. Harris, Johannes K. M. Knobloch and Holger Rohde: EMStaphylococcus Epidermidis /EMBiofilms: Functional Molecules, Relation to Virulence, and Vaccine Potential./P

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