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Frontiers of Nuclear Magnetic Resonance in Molecular Biology (UCLA Symposia on Molecular and Cellular Biology, New Series)

David Live

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ISBN 10: 0471567310 / ISBN 13: 9780471567318
Published by John Wiley & Sons Inc, 1990
Condition: Good Hardcover
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Title: Frontiers of Nuclear Magnetic Resonance in ...

Publisher: John Wiley & Sons Inc

Publication Date: 1990

Binding: Hardcover

Book Condition: Good

About this title


This volume examines the application of NMR techniques to molecular biology, including gene cloning and expression, site- specific mutagenesis, and biosynthetic isotopic labelling. It describes the broad-ranging applications of NMR techniques to the elucidation of structures at atomic resolution for moderately large systems. Investigators from a variety of disciplines cover the analysis of conformation, dynamics and interactions for a variety of molecules, including DNA, RNA, carbohydrates, peptides and proteins. Throughout the text, the contributors demonstrate the success of multi-dimensional NMR studies of biopolymers in solution. The book also examines possible NMR approaches for investigating systems where the molecule of interest does not reorient rapidly in solution. These systems possess molecules in the crystalline or hydrated solid state, part of supramolecular structures in solution, or are simply too large to reorient.

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