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This report provides a summary of procedures used in medically assisted conception, emphasizing what is known about the medical indications for specific procedures, their safety, and the factors influencing their success. Procedures covered include "in vitro" fertilization, gamete intrafallopian transfer, and similar procedures, as well as established techniques for artificial insemination. Addressed to the managers of programmes for the treatment of infertility, the book makes a special effort to distinguish procedures of demonstrated efficacy from those whose potential advantages remain unconfirmed. References to the literature are included. Background information provides an outline of the most common causes of infertility and the historic development of current techniques is summarized. Subsequent sections address the need to reduce the psychological stress linked to infertility and its treatment, and describe fundamental ethical principles that should govern programmes for medically assisted conception, particularly concerning protection of the human embryo and the use of human genetic material. Advances in "in vitro" fertilization are covered in five sections.Information includes an outline of the medical indications for treatment, followed by discussions of of the procedures and preferred protocols for the induction of multiple follicular development, for oocyte fertilization and subsequent embryo culture, and for the intrauterine and intrafallopian transfer. Details range from instructions for checking, maintenance and cleaning of laboratory items to a discussion of the dilemma created by the introduction of drug regimens that induce multiple follicular development and permit the harvest of numerous oocytes. Results of "in vitro" fertilization methods are reviewed in an effort to identify the factors affecting success. Artificial insemination is covered in three sections, which offer advice on the collection, storage and preparation of donor semen, outline indications and techniques, and provide guidance on the assessment of results. The remaining sections identify requirements for personnel, equipment, and quality assurance, as well as for future research in such areas as sperm abnormalities, oocyte quality, embryo culture, and cryopreservation.
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Book Description Stationary Office Books, 1992. Condition: Good. Former Library book. Shows some signs of wear, and may have some markings on the inside. Seller Inventory # GRP68670319
Book Description Stationary Office Books, 1992. Paperback. Condition: Used: Good. Seller Inventory # SONG9241208201