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Selection of a suitable analyticat method for estimation of individual drug in any multi-compound dosage form will always remain a challenge for an analytical chemist. The method so selected should provide analytical data as accurate as required, technically sound. Defensible with low limit of uncertainty and above all amenable to routine laboratory use and capable of being performed by personnel with minimum technical experience. Analytical methods for about 290 multi- component formulations in 18 chapters have been described with reasonable details to be reproduced without much difficulty, however, some degree of optimization and analytical skill may be required in certain cases. The methods for about 100 new formulations have been included while exhaustively revising- and up-dating the text. Methods which are obsolete have been deleted. Three additional chapters, i.e., Cardiac Drugs, Sedatives & Tranquillisers, and General Guidelines for Accreditation of Calibrating & Testing Laboratories with NABL, have been incorporated, the latter being extremely informative and useful for institutions seeking accreditation. Quality level of any analytical work primarily depends on the expertise of the analyst, based on the level of skill and practical experience attained; the analysts have been broadly grouped into five grades, enabling the quality control manager to assign analytical functions accordingly. Essential qualities of an analyst elaborated in the text should enable the analyst to evaluate his own performance periodically to maintain highest standards of analytical work.
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Dr.P.D. Sethi obtained his Ph.D. from madras university, Madras, India. He has been pursuning his analytical career since last 30 years. All the books authored by him are on practical application of different analytical techniques for analysis of multi-component drug formulations. these books are the only kind on the subject. while serving as chairman, ayurvedic pharmacopoeia of india, Dr. Sethi was instrumental in adopting TLC for finger-print profiling of medicinal plants for their correct identification. it is often said that library of any analytical laboratory, pharmaceutical institute and pharma industry is incomplete without books authored by Dr. Sethi.Synopsis:
The methods for about 100 new formulations have been included while revising and updating the text. The book also covers good laboratories, general requirements, analytical procedures and analyst validation.
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