Epilepsies are characterised by chronically and spontaneously recurring seizures. In the last twenty years, intensive scientific investigations have led to a considerable improvement in diagnostics, which is considered a fundamental precondition for improved treatment of epilepsies. Epilepsies that cannot be sufficiently controlled by monotherapy of one type of antiepileptic medication are considered often difficult to treat and therefore have an unfavourable prognosis. According to the seizure type and/or epileptic syndrome, a more or less intensive pharmacotherapy with one or more adequately applied antiepileptic drugs is suggested for treatment. Despite application of this antiepileptic treatment, there still remains a considerable number of patients whose seizures cannot be controlled satisfactorily. For these patients, new antiepileptic drugs offer a new possiblity of treatment or, as another alternative, epilepsy surgery. However, the surgical treatment of epilepsy, being an irreversible measure, is not an alternative for all patients whose types of epilepsies are resistant to pharmacotherapy. Therefore, the development of new antiepileptic drugs is an important challenge for the treatment of epilepsy.
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Epilepsies are characterised by chronically and spontaneously recurring seizures. In the last 20 years intensive scientific investigations have lead to a considerable improvement of diagnostics, which is to be considered a
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