Comparative Genomics and Drug Design Strategies: A Bioinformatics Approaches Based Study of Malaria Parasites - Softcover
Synopsis
Malaria is a threat to mankind and responsible for millions of cases of morbidity and mortality worldwide. Plasmodium parasite is responsible for causing disease. This work investigates and reveals the hidden information inside the parasite genomes using comparative genome analysis and codon usage bias study. The possibility of using variable surface proteins as a common drug target has been checked in both the human infecting Plasmodium species and it was found that variable surface proteins cannot be used as a common drug target due to existence of sequential and structural differences at both the genome and proteome level. Metabolic network information is also utilized in this piece of work for identifying new drug targets. Further in silico approaches viz. molecular modeling, structure-based 3D pharmacophore model generation, virtual screening and docking etc. were also utilized to find the drug prototypes.
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Comparative Genomics and Drug Design Strategies
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LAP LAMBERT Academic Publishing Jan 2015, 2015
ISBN 10: 3659683620
ISBN 13: 9783659683626
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Malaria is a threat to mankind and responsible for millions of cases of morbidity and mortality worldwide. Plasmodium parasite is responsible for causing disease. This work investigates and reveals the hidden information inside the parasite genomes using comparative genome analysis and codon usage bias study. The possibility of using variable surface proteins as a common drug target has been checked in both the human infecting Plasmodium species and it was found that variable surface proteins cannot be used as a common drug target due to existence of sequential and structural differences at both the genome and proteome level. Metabolic network information is also utilized in this piece of work for identifying new drug targets. Further in silico approaches viz. molecular modeling, structure-based 3D pharmacophore model generation, virtual screening and docking etc. were also utilized to find the drug prototypes. 144 pp. Englisch. Seller Inventory # 9783659683626
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Comparative Genomics and Drug Design Strategies
Published by
LAP LAMBERT Academic Publishing, 2015
ISBN 10: 3659683620
ISBN 13: 9783659683626
New
Softcover
Seller: moluna, Greven, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Yadav Manoj KumarDr. Manoj Kumar Yadav recieved his Ph.D. degree in Bioinformatics from Banaras Hindu University, Varanasi, India. Dr. Yadav is presently serving as an Assistant Professor (Bioinformatics) in Department of Biochemistr. Seller Inventory # 15939345
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Comparative Genomics and Drug Design Strategies
Published by
LAP LAMBERT Academic Publishing Jan 2015, 2015
ISBN 10: 3659683620
ISBN 13: 9783659683626
New
Taschenbuch
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Malaria is a threat to mankind and responsible for millions of cases of morbidity and mortality worldwide. Plasmodium parasite is responsible for causing disease. This work investigates and reveals the hidden information inside the parasite genomes using comparative genome analysis and codon usage bias study. The possibility of using variable surface proteins as a common drug target has been checked in both the human infecting Plasmodium species and it was found that variable surface proteins cannot be used as a common drug target due to existence of sequential and structural differences at both the genome and proteome level. Metabolic network information is also utilized in this piece of work for identifying new drug targets. Further in silico approaches viz. molecular modeling, structure-based 3D pharmacophore model generation, virtual screening and docking etc. were also utilized to find the drug prototypes.Books on Demand GmbH, Überseering 33, 22297 Hamburg 144 pp. Englisch. Seller Inventory # 9783659683626
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Comparative Genomics and Drug Design Strategies : A Bioinformatics Approaches Based Study of Malaria Parasites
Published by
LAP LAMBERT Academic Publishing, 2015
ISBN 10: 3659683620
ISBN 13: 9783659683626
New
Taschenbuch
Seller: AHA-BUCH GmbH, Einbeck, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Malaria is a threat to mankind and responsible for millions of cases of morbidity and mortality worldwide. Plasmodium parasite is responsible for causing disease. This work investigates and reveals the hidden information inside the parasite genomes using comparative genome analysis and codon usage bias study. The possibility of using variable surface proteins as a common drug target has been checked in both the human infecting Plasmodium species and it was found that variable surface proteins cannot be used as a common drug target due to existence of sequential and structural differences at both the genome and proteome level. Metabolic network information is also utilized in this piece of work for identifying new drug targets. Further in silico approaches viz. molecular modeling, structure-based 3D pharmacophore model generation, virtual screening and docking etc. were also utilized to find the drug prototypes. Seller Inventory # 9783659683626