Understanding ME/CFS & Strategies for Healing - Softcover

Ussher, Patrick

Softcover

ISBN 10: 2959831004 ISBN 13: 9782959831003

Publisher: In Spem Publications, 2025

Synopsis

If you live with relentless exhaustion, post-exertional malaise (PEM), brain fog or “normal” test results that explain nothing, this book will finally help you understand what’s really going on.

Millions with ME/CFS, Long Covid, and post-viral fatigue are told their symptoms are a mystery. But emerging research may at last reveal the underlying mechanisms — and offer a path toward meaningful improvement.

In this clear, direct, and deeply hopeful guide, ME/CFS patient Patrick Ussher explains the breakthrough model proposed by Professors Klaus Wirth and Carmen Scheibenbogen. Their work brings together the major abnormalities seen in ME/CFS — low blood volume, microclots, autonomic dysfunction, mitochondrial impairment, autoimmunity, and more — into one interconnected cycle.

It may finally explain why activity triggers PEM, why rest doesn’t restore energy, and why so many develop chronic fatigue after a viral illness.

This book goes far beyond theory. It offers practical tools, science-based insights, and real-world strategies that patients use to manage symptoms and improve quality of life.

Inside, you’ll learn about:

• Breathing techniques to improve oxygenation

• Ancestral nutrition and gut repair

• Microclot-oriented treatment approaches

• Blood-washing procedures (HELP Apheresis & Immunoadsorption)

• The Perrin Technique (for spinal & lymphatic health)

• The strengths and limits of neuroplasticity (“brain retraining”)

• Pacing, PEM management, and mitochondrial support

• The potential “Mitodicure” pill which could become the world's first ME/CFS-specific medication

Patrick also shares his own ME/CFS journey with honesty and clarity: what has helped him, what has not, and how he learned to navigate a misunderstood illness with both realism and hope.

If you live with:

• ME/CFS

• Long Covid

• post-viral fatigue

• dysautonomia / POTS

• unexplained fatigue with normal blood tests

…this book will give you a clear framework for understanding your symptoms and practical strategies that might help you feel better.

Straightforward. Evidence-based. Patient-centred.

A guide for anyone seeking answers about the most mysterious of illnesses.

Includes a foreword by Prof. Klaus Wirth who is developing the Mitodicure medication.

Important information: regarding audiobook version (narrated with Amazon's Virtual Voice)

This can be found if you search for the book on audible.com. Readers all around the world can find and listen to the book there (though it is not available directly on audible.co.uk, .fr, etc...)

About this title

About the Authors

Patrick Ussher has had ME/CFS for seven years. He has a YouTube channel, 'Understanding ME-CFS', in which he talks about the research into ME/CFS and Long Covid in an accessible way and in which he shares treatment strategies that he has tried. He has also written a medical hypothesis on the potential causes of excessive thirst in ME/CFS and Long Covid and why this symptom has likely been historically misdiagnosed as 'psychogenic water drinking' (available as a free download from: www.themythofprimarypolydipsia.com). He also gives regular talks to patient groups such as The Irish ME Trust and has written for the ME/CFS blog, Health Rising, on various topics. Patrick has also written a book which compares Stoicism and Buddhism (Stoicism and Western Buddhism: A Reflection on Two Philosophical Ways of Life) and edited several books on modern-day applications of Stoic philosophy (Stoicism Today: Selected Writings, Volumes One & Two). In 2018, he worked with Columba Press to publish a new version of his late mother's book on coping with breast cancer, titled: 'Following the Pink Ribbon Path'. He has a BA and MA in Classics (Ancient Greek and Latin) from The University of Exeter. He is also the composer of music in a contemporary classical style and is part of the online Artlist catalogue. His music can be listened to on Spotify. Patrick is from Ireland and has lived in both Ireland and France over the course of his illness.

Prof. Dr. Klaus Wirth, Medical Doctor, PhD, has served as Chief Scientific Officer and Managing Director of Mitodicure since 2022. He was previously Senior Researcher at Sanofi in Germany which he joined in 1984. Klaus worked as a pharmacologist in the fields of cardiovascular, bradykinin antagonism, cerebral blood flow, stroke, heart failure, arrhythmias, sodium-calcium exchanger NCX blockers, endocrinology, diabetes, obstructive sleep apnea, dysphagia, and immunology. Approximately 70 patents are attributable to his work, as well as five clinical developmental projects, one of which Firazyr(TM), a drug for the treatment of acute attacks of hereditary angioedema, has reached the market. Klaus was co-founder of KOSA Pharma GmbH. He is adjunct professor at the Institute of Pharmacology at Goethe University Frankfurt, Germany.

Edition details

• Publisher: In Spem Publications
• Publication date: 2025
• Language: English
• ISBN 10: 2959831004
• ISBN 13: 9782959831003
• Binding: Paperback
• Number of pages: 440