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Epilepsy in pregnancy poses a serious threat to the mother and to her developing child. Even in previously well-controlled epilepsy, physiological changes in the mother during pregnancy and also during labour and delivery can alter the pharmacokinetic drug (AED) therapy causing increased seizure frequency. The threats to the foetus include the seizures themselves and the mother's loss of consciousness, the AEDs, many of which are high teratogenic causing malformations and development abnormalities, and the risk of inheriting epilepsy. This work deals comprehensively with these and related issues, such as prenatal screening and diagnosis of abnormalities, effects of vitamin supplementation and AEDs and breast feeding. The authors discuss the latest findings from research, and offer guidance for the clinical management of these patients for whom a delicate balance must be weighed between the need to control seizures in the mother against the potential risk to the foetus.
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Book Description Routledge, 1997. Condition: New. book. Seller Inventory # M187181636X