Items related to The Principles and Practice of Medicine
This historic book may have numerous typos, missing text or index. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. 1909. Not illustrated. Excerpt: ... VI. SCLERODERMA. Definition.--A condition of localized or diffuse induration of the skin. Lewin and Heller (Die Sclerodermie, Berlin, 1895) have recently collected from the literature 508 cases. Two forms are recognized: the circumscribed, which corresponds to the keloid of Addison, and to morphcea; and the diffuse, in which large areas are involved. The disease affects females more frequently than males. The cases occur most commonly at the middle period of life. The sclerema nconalorum is a different affection, not to be confounded with it. The disease is more common in the United States than statistics indicate. I have had 20 cases under observation in the past fifteen years. In the circumscribed form there are patches, ranging from a few centimetres in diameter to the size of the hand or larger, in which the skin has a waxy or dead-white appearance, and to the touch is brawny, hard, and inelastic. Sometimes there is a preliminary hyperaemia of the skin, and subsequently there are changes in color, either areas of pigmentation or of complete atrophy of the pigment--leucoderma. The sensory changes are rarely marked. The secretion of sweat is diminished or entirely abolished. The disease is more common in women than in men, and is situated most frequently about the breasts and neck, sometimes in the course of the nerves. The patches may develop with great rapidity, and may persist for months or years; sometimes they disappear in a few weeks. The diffuse form, though less common, is more serious. It develops first in the extremities or in the face, and the patient notices that the skin is unusually hard and firm, or that there is a sense of stiffness or tension in making accustomed movements. Gradually a diffuse, brawny induration develops and the skin becomes f...
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- PublisherGeneral Books LLC
- Publication date2012
- ISBN 10 123521351X
- ISBN 13 9781235213519
- BindingPaperback
- Number of pages650
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