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This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation. Completely revised and expanded, this Third Edition contains the knowledge necessary to apply endotoxin testing in the increasingly complex pharmaceutical environment, featuring sections detailing the latest information regarding clinical advances, regulation standards, and validation procedures for computerized kinetic tests.
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"Praise for the previous edition... ...a valuable addition to the literature....combines the practical and theoretical aspects of pyrogens and endotoxins and their detection....serve[s] very well as a resource for those interested in pursuing one or more specific facets of this complex and fascinating subject." ---Pharmacy International
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