Hematopoietic Stem Cell Transplantation - Hardcover

 
9780824702731: Hematopoietic Stem Cell Transplantation
Hardcover
ISBN 10: 0824702735 ISBN 13: 9780824702731
Publisher: CRC Press, 2000

Synopsis

This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more.
Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.
Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation

  • summarizes current understanding and development of clinical allogeneic HSC transplantation
  • discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation
  • considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors
  • details detection of bone marrow contamination by tumor cells and removal procedures
  • focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors
  • explores the effects of growth factor administration and leukapheresis on PB stem cell donors
  • shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use
  • reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells
  • employs automated fluorescence image cytometry to study early HSC behavior following seeding
    Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,

    • "synopsis" may belong to another edition of this title.

    About the Author

    Anthony D. Ho, Rainer Haas, Richard E. Champlin

    "About this title" may belong to another edition of this title.

    Publisher
    CRC Press
    Publication date
    2000
    Language
    English
    ISBN 10 
    0824702735
    ISBN 13 
    9780824702731
    Binding
    Hardcover
    Edition number
    1
    Number of pages
    620
    Editor
    Ho Anthony D., Haas Rainer, Champlin Richard E.

    Other Popular Editions of the Same Title

    9780367398316: Hematopoietic Stem Cell Transplantation

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    ISBN 10:  0367398311 ISBN 13:  9780367398316
    Publisher: Routledge, 2019
    Softcover