Physiological Pharmaceutics: Barriers to Drug Absorption - Hardcover

Washington, Neena; Washington, Clive; Wilson, Clive

Hardcover

ISBN 10: 0748405623 ISBN 13: 9780748405626

Publisher: CRC Press, 2000

Synopsis

In recent years, the emphasis in drug development has been the design of new delivery systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design the new dosage forms to overcome the body's barrier mechanisms which have specifically evolved to exclude foreign material.

This book provides an integrated approach to the study of drug formulation in the body with the emphasis on the formulation variables rather than the drugs. The link between physiology and pharmaceutics is presented to give an essential background of biological principles for the pharmacy student, pharmaceutical formulator and healthcare professional. Complex mathematical aspects of physical chemistry have been avoided to facilitate understanding, enabling the reader to concentrate on how the biological environment affects the performance of the drugs and dosage forms. As the majority of drugs are administered via the oral route a large proportion of the book is devoted to the gastrointestinal tract and the variation in the capacity for drug absorption which occurs along its length. Transdermal, ocular, pulmonary and nasal drug delivery are discussed in detail. New chapters in the book include 'Vaginal drug delivery', the 'Blood brain barrier' and 'Parenteral drug delivery'.

About this title

Review:

'Provides essential information...There is no equivalent source work.' '...a worthwhile and valuable contribution to this area.'

About the Author:

Washington; Neena University of Nottingham Medical School, England, UK,Washington; Clive AstraZeneca,Wilson; Clive University of Strathclyde, UK,

About this edition

• Publisher: CRC Press
• Publication date: 2000
• ISBN 10: 0748405623
• ISBN 13: 9780748405626
• Binding: Hardcover
• Edition number: 1
• Number of pages: 328