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Proteomic Biology Using LC/MS: Large Scale Analysis of Cellular Dynamics and Function: 15 (Wiley Series on Mass Spectrometry) - Hardcover

 
9780471662587: Proteomic Biology Using LC/MS: Large Scale Analysis of Cellular Dynamics and Function: 15 (Wiley Series on Mass Spectrometry)
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This is one of the first books to focus on the dynamic aspect of proteomes. The book introduces proteomics to the newcomer, reviews the theoretical aspects of proteomics and its state-of-the art technologies, along with a number of biological applications using "classical" proteomic technology. The book also presents a new concept, the Dynamome, or the expression of a comprehensive molecular set that participates in the whole dynamic process of a series of cellular events.

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Review:
"The book covers the topic of proteomics and mass spectrometry analysis well and does so at a reasonably advanced level. This volume would be suitable for advanced graduate students and for nonexpert scientists to learn about the application of mass spectrometry techniques for proteomic studies." (Quarterly Review of Biology, December 2008)
From the Back Cover:

A comprehensive guide to LC-MS applications that probe the dynamic aspectS of proteomes

The systematic identification and characterization of proteins and proteomes is one of the major interdisciplinary research areas of the life sciences in the post-genomic era. One of the primary goals of current proteomic research is the description of the composition, dynamics, and connections of the multi-protein "modules" and "machineries" that perform a wide range of biological functions in the cell. Proteomic Biology Using LC-MS: Large Scale Analysis of Cellular Dynamics and Function examines the latest LC-MS technologies in depth and explores their application to the analysis of the dynamic aspects of cellular function. After an overview of proteomics and proteomic technologies, it covers:

  • The basic aspects of LC-MS technology, including the principle of the method and assembly of the LC-MS system

  • Integrated LC-based MS methodologies coupled with quantitative methodologies and/or bioinformatics

  • The most recent applications, such as the analyses of signal transduction complexes following stimulation of cells and the analysis of the dynamic processes of ribosome biogenesis

  • A new concept, the "Dynamome," or the expression of a comprehensive molecular set that participates in the whole dynamic process of a series of cellular events

Detailed experimental examples help readers explore various applications in action. With comprehensive coverage of LC-MS technologies applicable to the analysis of dynamic cellular functions in proteomic scale, this is a unique reference for investigators and laboratory staffs in academic institutions and industries. It is also a valuable resource for students as well as for scientists in other fields who want to bridge the gap between their specialties and proteomic biology.

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  • PublisherWiley-Interscience
  • Publication date2007
  • ISBN 10 0471662585
  • ISBN 13 9780471662587
  • BindingHardcover
  • Edition number1
  • Number of pages264

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Nobuhiro Takahashi|Toshiaki Isobe|Dominic M. Desiderio|Nico M. Nibbering
Published by John Wiley & Sons (2007)
ISBN 10: 0471662585 ISBN 13: 9780471662587
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Book Description Condition: New. This is one of the first books to focus on the dynamic aspect of proteomes. The book introduces proteomics to the newcomer, reviews the theoretical aspects of proteomics and its state-of-the art technologies, along with a number of biological applications u. Seller Inventory # 556561921

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Shipping: £ 41.98
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