Principles of Genetics - Hardcover

Snustad, D. Peter; Simmons, Michael J.; Jenkins, John B.

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Hardcover

ISBN 10: 0471311960 ISBN 13: 9780471311966

Publisher: John Wiley & Sons, 1997

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This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

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From the Back Cover:

The cover shows many facets of genetics. Top row, Left: The DNA double–helix, here imaged in a scanning tunneling micrograph, is central to all genetics research. Right: Experimentation has shown that some social behaviors, such as nest cleaning by honeybees, is under genetic control. Second row, Left: Inherited disorders such as albinism, manifested here in a bullfrog, have provided many insights about the genetic control of metabolism. Right: Gregor Mendel′s 19th–century work with pea plants elucidated the basic principles of inheritance. Third row, Left: Efforts to combat HIV, the virus that causes AIDS, depend on knowing how the virus expresses its genes inside the cells of the immune system. Right: The fruit fly is ideally suited for studies on the genetic control of embryonic development and organ formation. Fourth row, Left: The identification of mutations that cause unregulated cell division facilitates the diagnosis, treatment, and prevention of breast cancer. Right: HeLa cells, derived in 1951 from Henrietta Lacks, a woman who died of cervical cancer, thrive in the laboratory and are used in research worldwide. Bottom row: The replication of chromosomes (left) is a prerequsite for cell division (right).

Synopsis:

That genetics is not a static body of knowledge is one of the fundamentals behind this text. Historical and contemporary experimental examples are therefore used throughout. The authors believe that genetics makes sense of evolution. Therefore, this volume presents concepts in an evolutionary context whenever possible. In addition, the text uses human examples to illustrate genetic concepts so that the student will see practical applications of genetic analysis. A study guide to accompany this text will be available (ISBN 0-471-15284-6).

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