This hands--on manual allows readers to gain a better understanding of organic reaction mechanisms by solving a wide range of problems. Answers for the problems are included along with mini--reviews that summarize and emphasize fundamental principles. This approach sharpens readersa reasoning ability and critical thinking.
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"I was very impressed by the high quality of the problems" "Grautas is to be congratulated for putting this book together." -- Journal of Chemical Education, June 2001
PREFACE
The primary goal of this book is to use organic mechanisms as a means of facilitating the mastery and understanding of the fundamental principles of organic chemistry, while at the same time sharpening a student’s reasoning ability and critical thinking. This is achieved through the judicious selection and use of a large number of problems selected from the chemical literature. Each question is meant to illustrate one or more fundamental principles of mechanistic organic chemistry. The level of difficulty and suitability of the questions in this book have been tested by including them in exams and/or as homework assignments in the undergraduate organic chemistry course (Part A), or the first year graduate-level course in organic chemistry (Part B).
Special emphasis has been placed on the organization of the book. Part A contains questions geared toward students taking the sophomore-level organic chemistry course. The questions and principles illustrated thereof, are organized in the same sequence as they are normally discussed in a standard textbook of organic chemistry. A series of mini reviews that summarize and reinforce fundamental principles that underlie a particular set of related problems have been included at the beginning of each set of questions. Thus, Part A can serve as a supplement to a standard textbook used in the first year organic chemistry course, and it is intended to meet an existing need, since only a token number of end-of-chapter mechanisms questions is included in most textbooks of organic chemistry.
The questions included in Part B are suitable for students in an honors course in organic chemistry, and beginning graduate students in chemistry, medicinal chemistry, biochemistry, and related disciplines. A limited number of applied problems has been included (Part C) to demonstrate how a knowledge og basic organic reaction mechanisms can be used to understand problems related to everyday life.
I am deeply indebted to Professor Richard A. Bunce (Oklahoma State University) for his diligence in reviewing the manuscript, and his many valuable comments. I am also grateful to Jennifer Yee for her editorial assistance, guidance and constant encouragement throughout the preparation of the workbook. Any errors that may have crept in are the sole responsibility of the author.
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