Principles of Organic Synthesis

9780416479508: Principles of Organic Synthesis
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The purpose of this book is to show how mechanistic principles can be applied both to acquiring a knowledge of organic synthetic processes and to planning the construction of organic compounds. It is designed for those who have had no more than a brief intoduction to organic chemistry amd who require a broad introduction to the subject. The book is in two parts. In part one, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions - chemical thermodynamcis, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In part two, these principles and concepts are applied to the formation of particular types of bonds, groupings and compounds: for example, how small molecules can be built on to give larger ones by the construction of new carbon-carbon bonds, or how one functional group can be transformed into another. The final chapter in part two describes the planning and detailed execution of the multi-step synthesis of several complex naturally occurring compounds. There have been numerous important developments since the second edition of this book was published 15 years ago, and every chapter has been brought up to date to include them. Among the more notable are: the stereochemical control of reactions, reflecting the need to synthesize efficiently compounds with several asymmetric centres; the use of organotransition-metal reagents, leading to a new chapter; the exploitation of lithium dilsopropylamide (LDA) as a base in the formation of new C-C bonds; free-radical reactions for the synthesis of C-C bonds; uses of organosilicon compounds; and subtle new protective and condensing reagents in polypeptide synthesis. An ELBS/LPBB edition is available

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9780412207600: Principles of Organic Synthesis (Science Paperbacks)

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ISBN 10:  0412207605 ISBN 13:  9780412207600
Publisher: Chapman and Hall, 1970

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R. Norman
Published by Methuen (1968)
ISBN 10: 0416479502 ISBN 13: 9780416479508
New Hardcover First Edition Quantity Available: 1
Irish Booksellers
(Portland, ME, U.S.A.)

Book Description Methuen, 1968. Condition: New. Andre Jandot (illustrator). book. Seller Inventory # M0416479502

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