Synopsis
Genes, Gene Products, and Transcription Factors.- Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair.- Cell Adhesion Molecules.- Apoptosis and Cell Death.- The Role of Mutation and Epimutation in the Development of Human Disease.- Bioinformatics and Omics.- General Approach to Molecular Pathology.- Applications in Anatomic Pathology.- Polymerase Chain Reaction and Reverse Transcription-Polymerase Chain Reaction.- Array Comparative Genomic Hybridization in Pathology.- Loss of Heterozygosity.- In Situ Hybridization: Principles and Applications.- Proteomics.- Immunohistochemistry of Biomarkers.- Basic Principles of Flow Cytometry.- Stem Cells.- Animal Models of Lung Disease.- Tissue Culture Models.
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Review
From the reviews:
"This book concisely presents basic concepts of molecular biology and applied molecular pathology. ... written for anyone interested in basic molecular pathology concepts. It would be of interest to physicians ... interested in adaptation of molecular biology concepts to pathologic diagnosis. It would also be of interest to those wanting a single reference to update their knowledge of molecular biology and applied molecular pathology. ... a great book for anyone wanting a concise and broad overview or review of molecular biology and applied molecular pathology." (Valerie L Ng, Doody’s Review Service, October, 2009)
From the Back Cover
The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine.
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