Smart Nanomaterials for Bioencapsulation (Micro and Nano Technologies) - Softcover

Softcover

ISBN 10: 032391229X ISBN 13: 9780323912297

Publisher: Elsevier, 2022

Synopsis

Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more.

Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, and more help determine the in vivo performance of the bioencapsulated food and drug derivatives.

• Outlines the major design principles surrounding the encapsulation of drugs, drug release, food and nutraceuticals at the nanoscale
• Discusses the pros and cons of different bioencapsulation methods for different application areas
• Outlines the major challenges of applying nanobioencapsulation at an industrial scale

About this title

About the Authors

Guillermo R. Castro is a Full Professor at the Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC), which is a partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG), at the Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Rosario, Santa Fe, Argentina. His areas of research are microbial and biomedical biotechnology, non-aqueous enzymology, bio-transformations. biopolymers (production and industrial uses), controlled release of molecules, nanobiotechnology, and hybrid materials.

Ashok Kumar is an Assistant Professor, in the Department of Biotechnology and Bioinformatics, at Jaypee University of Information Technology, Waknaghat, India. His research areas are in enzymology, biocatalysis, biopolymers, enzyme immobilization, and bioenergy.

Dr. Swati Sharma (MSc, Dr. Yashwant Singh Parmar University of Horticulture and Forestry, Nauni Solan H.P. India; PhD. University Malaysia, Pahang, Malaysia) is Assistant Professor at University Institute of Biotechnology, the Chandigarh University Mohali, India. She worked as a visiting researcher in the College of Life and Environmental Sciences at Konkuk University, Seoul, South Korea. She has also worked as a program co-coordinator at the Himalayan Action Research Center (HARC), Dehradun, and Senior Research Fellow at the India Agricultural Research Institute in 2013-2014. Presently, Dr. Sharma's research is in the field of bioplastics, hydrogels, keratin nano-fibers and nano-particles, biodegradable polymers and polymers with antioxidant and anticancer activities and sponges. Dr. Swati has published numerous books and papers in various internationally reputed journals.

Ram K. Gupta is a Professor in the Department of Chemistry at Pittsburg State University, USA. His research interests include green energy production and storage using conducting polymers, 2D materials, nanostructured materials and composites, polymers from renewable resources for industrial applications, polymer recycling for sustainable future, bio-compatible nanofibers and thin films for tissue regeneration, scaffolds, bio-degradable metallic implants, and antibacterial applications.

Tuan Anh Nguyen is a Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. He received a BS in physics from Hanoi University in 1992, a BS in economics from Hanoi National Economics University in 1997, and a PhD in chemistry from the Paris Diderot University, France, in 2003. He was a Visiting Scientist at Seoul National University, South Korea, in 2004, and the University of Wollongong, Australia, in 2005. He then worked as a Postdoctoral Research Associate and Research Scientist at Montana State University, United States in 2006-09. In 2012 he was appointed as the Head of the Microanalysis Department at the Institute for Tropical Technology. His research areas of interest include smart sensors, smart networks, smart hospitals, smart cities, complexiverse, and digital twins. He has edited more than 74 books for Elsevier, 12 books for CRC Press, 1 book for Springer, 1 book for RSC, and 2 books for IGI Global. He is the Editor-in-Chief of Kenkyu Journal of Nanotechnology & Nanoscience.

From the Back Cover

Bioencapsulation of food and drug derivatives is one of the promising approaches in modern pharmaceutical and nutrition science. The target delivery of pharmacological agents, as well as food additives under various conditions, requires the use of nanomaterials with particular properties. In this context, the systemic release of drug molecules, with minimum loss at non-target sites, also enhances the accumulation of diseased tissue or organs. Several smart nanomaterials have already been employed, to ensure the bioencapsulation of therapeutic drug agents, which results in enhanced specificity, efficiency, and speedy recovery from pathological conditions. Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, which degrade easily in the cellular compartment, determine the in vivo performance of the bioencapsulated food and drug derivatives.

This book focuses on the fundamentals, synthesis methods, and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. The delivery of genes, protein molecules, and antibiotics, through various advanced computer modulated techniques, will be discussed. The comparison between synthetic and biosynthetic systems, the potential of smart hybrid systems of nanoencapsulation will be highlighted in this book. The interesting aspects of multi-tasking encapsulation and enzyme- activated delivery will be discussed in individual chapters, and the use of these smart nanomaterials will also be highlighted.

Providing detailed information on the design and performance of advanced nanoencapsulation system, the book is an important reference source for biochemical engineers, chemists, and materials scientists.

Edition details

• Publisher: Elsevier
• Publication date: 2022
• ISBN 10: 032391229X
• ISBN 13: 9780323912297
• Binding: Paperback
• Language: English
• Number of pages: 296
• Editor: Castro, Nadda, Nguyen, Sharma, Gupta