Epigenetic Gene Expression and Regulation

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9780127999586: Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. * Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies* Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring* Chapters are replete with clinical examples to empower the basic biology with translational significance* Offers more than 100 illustrations to distill key concepts and decipher complex science

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Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0127999582 ISBN 13: 9780127999586
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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 235 x 190 mm. Language: English . Brand New Book. Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Bookseller Inventory # AA59780127999586

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Suming Huang, Michael D. Litt, Cynthia Ann Blakey
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Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0127999582 ISBN 13: 9780127999586
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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 235 x 190 mm. Language: English . Brand New Book. Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Bookseller Inventory # AA59780127999586

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Suming Huang, Michael D. Litt, Cynthia Ann Blakey
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Book Description Elsevier Science Publishing Co Inc. Hardback. Book Condition: new. BRAND NEW, Epigenetic Gene Expression and Regulation, Suming Huang, Michael D. Litt, Cynthia Ann Blakey, Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. * Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies* Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring* Chapters are replete with clinical examples to empower the basic biology with translational significance* Offers more than 100 illustrations to distill key concepts and decipher complex science. Bookseller Inventory # B9780127999586

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Book Description Hardback. Book Condition: New. Not Signed; Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to. book. Bookseller Inventory # ria9780127999586_rkm

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Book Description Book Condition: New. Depending on your location, this item may ship from the US or UK. Bookseller Inventory # 97801279995860000000

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Huang, Suming (Editor)/ Litt, Michael D. (Editor)/ Blakey, Cynthia Ann (Editor)
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Book Description Academic Pr, 2015. Hardcover. Book Condition: Brand New. 1st edition. 482 pages. 9.50x7.75x1.25 inches. In Stock. Bookseller Inventory # __0127999582

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