J. David Sweatt Mechanisms of Memory

ISBN 13: 9780126789577

Mechanisms of Memory

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9780126789577: Mechanisms of Memory

This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.

* Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems
* Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory
* Provides a balanced treatment of the strengths and weaknesses in modern experimental design

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Book Description:

Provides an overview of the cellular and molecular mechanisms involved in learning and memory.

From the Back Cover:

Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer's Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

  • Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
  • Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
  • Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
  • A companion website provides figures in PowerPoint format plus additional, detailed further reading references

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J. David Sweatt
Published by Academic Press (2003)
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