Mechanisms of Memory - Hardcover

Sweatt, J. David

Hardcover

ISBN 10: 0126789576 ISBN 13: 9780126789577

Publisher: Academic Press, 2003

Synopsis

This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.

* Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems
* Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory
* Provides a balanced treatment of the strengths and weaknesses in modern experimental design

About this title

Review:

"The book is well written and includes interesting and illustrative text inserts as well as colorful fugures with detailed explanations. Mechanisms of Memory is a successful integration of recent discoveries and technological advances applied to learning and memory at many different levels that will appeal to its target audience of advanced undergraduates and graduates across a number of disciplines."
--AMERICAN JOURNAL OF PSYCHIATRY (November 2005, 162:11)

"This is an exceptional book in more than one aspect. David Sweatt has written a monograph in which long term potentiation (LTP) is central issue. However, this book is not an endless presentation of all the numerous experiments into a context of learning and memory...the book presents a real opportunity for the advanced student, and the interested scientists, to learn more about LTP and how to put it into a perspective...The illustrations in the book are of high quality, informative and to the point. Every chapter is introduced at an abstract level, the last item I wanted to mention which makes this a special book, bringing long term reminiscences of Rothko and Pollock."
- Journal of Chemical Neuroanatomy (2005)

From the Back Cover:

Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer’s Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

• Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
• Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
• Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
• A companion website provides figures in PowerPoint format plus additional, detailed further reading references

|

Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer’s Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

• Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
• Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
• Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
• A companion website provides figures in PowerPoint format plus additional, detailed further reading references

About this edition

• Publisher: Academic Press
• Publication date: 2003
• ISBN 10: 0126789576
• ISBN 13: 9780126789577
• Binding: Hardcover
• Number of pages: 350