Molecular epidemiology utilizes the same paradigm as traditional epidemiology, but uses biological markers to identify exposure, disease or susceptibility. This book presents the epidemiologic methods pertinant to biological markers. It is designed to enumerate the considerations necessary for valid field research and provides a resource on the salient features of biological indicators. This book should be of interest to graduate students and researchers in epidemiology and molecular biology, cancer researchers and medical residents.
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"The book is an excellent review of the crucial issues related to the incorporation of new markers of exposure, disease, or susceptibility into epidemiologic investigations... This book is an excellent resource for all researchers involved in the quest to understand the determinants of disease and apply this knowledge to the maintenance of the health of the public."
--SCIENCE
This book serves as a primer for laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology builds on the developments and techniques of molecular biology, providing powerful tools to supplement or improve epidemiological research to identify exposure, disease, or susceptibility in human populations. It assists traditional epidemiologists in reducing misclassification, understanding mechanisms, and identifying risks to individuals and groups.
Molecular Epidemiology is a compendium of the principles for and practice of Molecular epidemiology. Focusing on methods for using biological markers in epidemiological research, this book explores markers relevant to a broad range of organ and disease systems research. It enumerates the considerations necessary for valid field research and provides a resource on the salient and subtle features of biomarkers. The book also includes discussions of statistics and validation, a review of issues pertaining to specimen collection, and a look at the sociological implications of using biological markers in epidemiological research.
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