Crystallography Made Crystal Clear: A Guide for Users of Macromolecular Models (Complementary Science)

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9780125870757: Crystallography Made Crystal Clear: A Guide for Users of Macromolecular Models (Complementary Science)

Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists.
Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background
Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallography
Explains how to read crystallography papers in research journals
If you use computer-generated models of proteins or nucleic acids for:
Studying molecular interactions
Designing ligands, inhibitors, or drugs
Engineering new protein functions
Interpreting chemical, kinetic, thermodynamic, or spectroscopic data
Studying protein folding
Teaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.

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Book Description:

Expanded and updated edition uses four-color art and concise language to explain the basis of X-ray crystallography

From the Back Cover:

Gale Rhodes makes crystallography accessible to readers who have no prior knowledge of the field, or its mathematical basis. The second edition of Crystallography Made Crystal Clear has been fully updated and expanded to make it the most comprehensive and concise reference for beginning crystallographers. The book also introduces essential World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. The CMCC Home Page (www.usm.maine.edu/~rhodes/CMCC) provides access to all tools and links to all resources discussed in this book. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers.
Key Features
* Provides clear, understandable descriptions of principles of X-ray crystallography
* Leads reader through unintimidating and thorough explanations of the underlying mathematics
* Provides abundant illustrations, including diagrams, charts, photographs, and color stereo
* images
* Explains how to read crystallography papers in research journals
* Includes brief descriptions of other diffraction methods (neutron, electron, Laue) and the kinds
* of structural information they can provide
* Introduces other methods of macromolecular structure determination (NMR spectroscopy and
* homology modeling), and provides guidance in judging the quality of these models

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