Bones and Cartilage, Second Edition: Developmental and Evolutionary Skeletal Biology

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9780124166783: Bones and Cartilage, Second Edition: Developmental and Evolutionary Skeletal Biology

Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail.

The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research.

  • Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations
  • Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning
  • Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages
  • Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms)
  • Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data
  • Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

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About the Author:

I have been interested in and studying skeletal tissues since my undergraduate days in Australia in the 1960s. Those early studies on the development of secondary cartilage in embryonic birds, first published in 1967, have come full circle with the discovery of secondary cartilage in dinosaurs12. Bird watching really is flying reptile watching. Skeletal tissue development and evolution, the embryonic origins of skeletal tissues (especially those that arise from neural crest cells), and integrating development and evolution in what is now known as evo-devo have been my primary preoccupations over the past 50+ years.

Review:

"...gives an updated impressive overview that integrates development and evolution of the skeleton and covers of a tremendous wealth of various topics...An impressive achievement that sets standards." --Bulletin of Fish Biology

"I would recommend this book for all graduate students in the health sciences, and as a dentist I would specifically recommend it to the dental specialties: orthodontists, endodontists, oral surgeons, periodontists, and oral pathologists. The information is presented in a clear concise manner with ample figures and extensive references. As a practicing periodontist with over 30 years of experience, I have found this book both useful and engaging. It now has a prominent position among my desk reference books. It is one that I will visit on a regular and frequent basis." - William Stenberg, DDS, MS, MPH, Diplomate of the American Board of Periodontology Rockmore-King Clinic Kodiak, AK, USA

“This is the book that will set the standard for the field for decades to come. It covers everything from the elementary to the highly sophisticated and the obscure detail. This is a great resource! - Gunter Wagner, Professor of Ecology and Evolutionary Biology, Yale University

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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 2nd edition. Language: English . Brand New Book. Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Bookseller Inventory # LIB9780124166783

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