Gene Therapy for Viral Infections - Hardcover

Arbuthnot, Patrick

Hardcover

ISBN 10: 0124105181 ISBN 13: 9780124105188

Publisher: Academic Press, 2015

Synopsis

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. 

Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors.

Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology.

• Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections
• Bridges the gap between the basic science and the important medical applications of this technology
• Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering
• Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs
• Arms the reader with the cutting-edge information needed to stay abreast of this developing field

About this title

Review:

Offers considerations for employing gene therapy and synthetic nucleic acids to achieve antiviral effects

From the Back Cover:

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid used to treat viral infections, bridging the gap between the basic science and important clinical applications of this technology. Coverage begins with exploration of the fundamentals and harnessing RNAi to silence viral gene expression. Topics of antiviral gene editing, viral gene therapy vectors, and non-viral vectors follow. Subsequent detailed coverage of developing use of gene therapy to treat specific infections expands coverage of application of the technology.

This systematic integrated review of advances in nucleic acid-based antiviral drugs discusses potential advantages of this new technology over current treatment options. Principles of rational design of antivirals and hurdles that currently face the technology are addressed. Aiming to elucidate the challenges and benefits of Gene Therapy for Viral Infections, this work arms the reader with the cutting-edge information needed to stay abreast of this developing field.

About this edition

• Publisher: Academic Press
• Publication date: 2015
• ISBN 10: 0124105181
• ISBN 13: 9780124105188
• Binding: Hardcover
• Number of pages: 392