Metagenomics for Microbiology

ISBN 13: 9780124104723

Metagenomics for Microbiology

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9780124104723: Metagenomics for Microbiology

Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. * Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studies* Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose* Presented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications.

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We are now realizing both as a scientific community and a society that we are not living alone in our body. For each of our human cells, we are hosting in harmony 10 microbes. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. Concisely discussing the practical uses of high throughput analysis to move our understanding of biological principles, this book provides a solid base for the design of metagenomic studies, with the objective of aiding successful phylometagenomic, whole shotgun metagenomic, and transcriptomic studies across the multiplying audiences within molecular biology, microbiology, genomic expression, infectious disease, and cancer research. * Expertly describes present-day methodologies with best-practice prescription, from sample to data analysis, for current metagenomic studies* Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose and heavy-going methologies* Interdisciplinary and translational approach ranges across sample preparation, data production, data clean up, data analysis, statistics and experimental biology with accompanying descriptions for varied research populations and complementary viewpoints

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Metagenomics for Microbiology

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Maria Rivera, Jacques Izard
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Book Description Elsevier Science Publishing Co Inc. Paperback. Book Condition: new. BRAND NEW, Metagenomics for Microbiology, Maria Rivera, Jacques Izard, Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. * Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studies* Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose* Presented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications. Bookseller Inventory # B9780124104723

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IZARD, JACQUES; RIVERA, MARIA
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IZARD, JACQUES; RIVERA, MARIA
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Book Description Oxford Elsevier LTD Okt 2014, 2014. Taschenbuch. Book Condition: Neu. 228x151x12 mm. Neuware - Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. 144 pp. Englisch. Bookseller Inventory # 9780124104723

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