Translational Neuroimaging

0 avg rating
( 0 ratings by GoodReads )
 
9780123869456: Translational Neuroimaging

"Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. It provides a background to translational research and the use of brain imaging in neuropsychiatric disorders. It includes critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers. It identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders. It features an accompanying website with additional images and text.

"synopsis" may belong to another edition of this title.

Review:

"This book examines how neuroimaging can play a role in translational research by developing preclinical models and ultimately clinical studies for drug discovery."--Doody.com, October 17, 2013 "Researchers in imaging technology, neurology, and mental health sciences introduce fundamental concepts of neuroimaging, the various modalities being used, how it is being used to study central nervous system (CNS) disorders, and specifically how it is being used to discover and develop drugs for such disorders."--Reference & Research Book News, October 2013

About the Author:

Dr. McArthur began his professional career investigating the role of serotonin on feeding behaviour at the Clarke Institute of Psychiatry in Toronto, Canada. This interest led him to complete a PhD in the psychopharmacology of feeding behaviour and macronutrient selection with John Blundell at the University of Leeds, Leeds, UK. In 1981 he joined Beecham Pharmaceuticals to work on adrenergic involvement in energy expenditure and obesity. In 1983 Dr McArthur began working on M1 functional agonists for the treatment of Alzheimer disease and was responsible for demonstrating the initial procognitive effects of Sabcomeline. Following the merger of Beecham with SmithKline French, Dr McArthur was appointed Business Development Executive at I.T.E.M-Labo, Paris working with Roger Porsolt in behavioural pharmacology contract research. In 1992, Robert was appointed Head of Behavioral Pharmacology at Farmitalia Carlo Erba, later Pharmacia in Milan. His lab was responsible for the preclinical behavioural pharmacology of Sabcomeline (Alzheimer's and schizophrenia); Safinamide (epilepsy and Parkinson's); Reboxetine (depression); Cabergoline (Parkinson's); Nicergoline (Mild Cognitive Impairment); and Amperozide (alcoholism). He is listed as an inventor in 19 issued patents and applications of which he is the principal inventor in 3. In 1998, Robert transferred to the Pharmacia and Upjohn Company in Kalamazoo, Michigan where as senior behavioural pharmacologist responsible, he worked on mutant mouse characterizations, the establishment of a primate unit assessing cognitive changes in monkeys (CANTAB), and development of anxiety models in marmosets. Soon after the merger of Pharmacia and Upjohn with Monsanto-Searle, Robert returned to Europe where in 2001 he founded the consulting company, McArthur and Associates GmbH in Basel. Robert has since worked on a series of projects for both large Pharma as well as biotechs, including further primate work in Parkinson's, development of behavioural pharmacology expertise, novel target validation, due diligence, medical writing, strategy evaluation, scientific advisor and as an expert witness. Dr McArthur has pursued his academic interests in translational neuroscience. In 2003, Robert was appointed as a visiting Associate Research Professor in the Department of Neuroscience (Division of Behavioural Neuroscience) at the Karolinska Institute in Stockholm. He has written and co-edited extensively on the subject of the clinical and translational relevance of animal models of CNS disorders. He has authored 43 peer-reviewed papers, 13 book chapters, co-author on 1 book and senior editor of a three-volume set on translational value of animal models for CNS drug discovery. He has served as section editor (CNS) for Current Opinion in Investigational Drugs and is on the editorial board of Drugs of the Future. In 2009 he was appointed an independent scientific expert evaluator for the European FP7-Health call.

"About this title" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

McArthur, Robert
Published by Elsevier Science Publishing Co Inc, United States (2013)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 10
Seller
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. New.. 236 x 193 mm. Language: English . Brand New Book. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. It provides a background to translational research and the use of brain imaging in neuropsychiatric disorders. It includes critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers. It identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders. It features an accompanying website with additional images and text. Bookseller Inventory # AA59780123869456

More Information About This Seller | Ask Bookseller a Question

Buy New
88.68
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

2.

McArthur, Robert
Published by Elsevier Science Publishing Co Inc, United States (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 10
Seller
The Book Depository US
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2012. Hardback. Book Condition: New. New.. 236 x 193 mm. Language: English . Brand New Book. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Bookseller Inventory # AA59780123869456

More Information About This Seller | Ask Bookseller a Question

Buy New
90.80
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

3.

McArthur, Robert
Published by Academic Press 1, United States
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
Powell's Books
(Portland, OR, U.S.A.)
Rating
[?]

Book Description Academic Press 1, United States. Hardcover. Book Condition: New. HARDCOVER Legendary independent bookstore online since 1994. Reliable customer service and no-hassle return policy. New Arrivals. Book: NEW, New. Bookseller Inventory # 64978012386945600. Bookseller Inventory # 64978012386945600

More Information About This Seller | Ask Bookseller a Question

Buy New
110.65
Convert Currency

Add to Basket

Shipping: 3.63
Within U.S.A.
Destination, Rates & Speeds

4.

McArthur, Robert
Published by Academic Press (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
Irish Booksellers
(Rumford, ME, U.S.A.)
Rating
[?]

Book Description Academic Press, 2012. Hardcover. Book Condition: New. book. Bookseller Inventory # 0123869455

More Information About This Seller | Ask Bookseller a Question

Buy New
119.44
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

5.

McArthur, Robert
Published by Academic Pr (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 2
Seller
Revaluation Books
(Exeter, United Kingdom)
Rating
[?]

Book Description Academic Pr, 2012. Hardcover. Book Condition: Brand New. 1st edition. 421 pages. 10.00x8.00x1.00 inches. In Stock. Bookseller Inventory # __0123869455

More Information About This Seller | Ask Bookseller a Question

Buy New
117.57
Convert Currency

Add to Basket

Shipping: 6
From United Kingdom to U.S.A.
Destination, Rates & Speeds

6.

McArthur, Robert
Published by Academic Press (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Academic Press, 2012. Hardback. Book Condition: NEW. 9780123869456 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE0893253

More Information About This Seller | Ask Bookseller a Question

Buy New
132
Convert Currency

Add to Basket

Shipping: 8.04
From United Kingdom to U.S.A.
Destination, Rates & Speeds

7.

McArthur, Robert
Published by Academic Press (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Academic Press, 2012. Hardback. Book Condition: NEW. 9780123869456 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE01197183

More Information About This Seller | Ask Bookseller a Question

Buy New
132
Convert Currency

Add to Basket

Shipping: 8.04
From United Kingdom to U.S.A.
Destination, Rates & Speeds

8.

McArthur, Robert
Published by Academic Pr (2012)
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
Revaluation Books
(Exeter, United Kingdom)
Rating
[?]

Book Description Academic Pr, 2012. Hardcover. Book Condition: Brand New. 1st edition. 421 pages. 10.00x8.00x1.00 inches. In Stock. Bookseller Inventory # z-0123869455

More Information About This Seller | Ask Bookseller a Question

Buy New
157.16
Convert Currency

Add to Basket

Shipping: 6
From United Kingdom to U.S.A.
Destination, Rates & Speeds

9.

McArthur, Robert
Published by Elsevier Science Publishing Co Inc
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
THE SAINT BOOKSTORE
(Southport, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc. Hardback. Book Condition: new. BRAND NEW, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment, Robert A. McArthur, "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. It provides a background to translational research and the use of brain imaging in neuropsychiatric disorders. It includes critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers. It identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders. It features an accompanying website with additional images and text. Bookseller Inventory # B9780123869456

More Information About This Seller | Ask Bookseller a Question

Buy New
159.06
Convert Currency

Add to Basket

Shipping: 5.94
From United Kingdom to U.S.A.
Destination, Rates & Speeds

10.

McArthur, Robert
ISBN 10: 0123869455 ISBN 13: 9780123869456
New Hardcover Quantity Available: 1
Seller
AussieBookSeller
(SILVERWATER, NSW, Australia)
Rating
[?]

Book Description 2012. Hardcover. Book Condition: New. 191mm x 235mm x. Hardcover. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique colla.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 464 pages. 1.122. Bookseller Inventory # 9780123869456

More Information About This Seller | Ask Bookseller a Question

Buy New
172.76
Convert Currency

Add to Basket

Shipping: 22.62
From Australia to U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book