Molecular Pathology: The Molecular Basis of Human Disease

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9780123744197: Molecular Pathology: The Molecular Basis of Human Disease

Most "pathology" textbooks cover diseases and disease processes from the perspective of description (what does it look like and what are its characteristics), risk factors, disease-causing agents, and to some extent, cellular mechanisms. However, these books typically contain very sparse coverage (if any at all) of molecular mechanisms of disease. The reason for this is partially historical - most major forms of disease have been known for a long time, but the molecular basis of these diseases are not always known or have been elucidated only recently. Nevertheless, our overall understanding of the molecular and genetic mechanisms of the pathogenesis of most major human diseases has been advancing at a significant pace over the last two decades. As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, there is a need for a textbook where molecular mechanisms represent the focus. Molecular Pathology focuses on the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. Molecular Pathology is appropriate as a classroom teaching tool for medical students, biomedical graduate students, and some allied health students. In addition, it should be used as a reference book for practicing basic scientists and physician scientists that perform disease-related research. Further, this textbook will be valuable for pathology residents and other postdoctoral fellows who need to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. * Exam Master web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site - will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of "integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of "molecular medicine and the translational aspects of molecular pathology

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Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of "molecular pathogenesis" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site - will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of "integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of "molecular medicine and the translational aspects of molecular pathology

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Molecular Pathology will be the first textbook for introductory pathology courses in Ph.D. and medical school programs that fully incorporates molecular coverage. Since the mapping of the human genome most biomedical fields have migrated to more molecular approaches to the science. The same is true for pathology however the textbooks have not yet caught up with this trend. This will be the first introductory pathology textbook that truly integrates the molecular mechanisms of human disease. * Exam Master(r) web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site - will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of "molecular medicine" and the translational aspects of molecular pathology

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Published by Elsevier Science Publishing Co Inc, United States (2009)
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Book Description Elsevier Science Publishing Co Inc, United States, 2009. Hardback. Book Condition: New. 274 x 224 mm. Language: English . Brand New Book. Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of molecular pathogenesis of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. Bookseller Inventory # AA59780123744197

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Published by Elsevier Science Publishing Co Inc, United States (2009)
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Book Description Elsevier Science Publishing Co Inc, United States, 2009. Hardback. Book Condition: New. 274 x 224 mm. Language: English . Brand New Book. Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of molecular pathogenesis of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. Bookseller Inventory # AA59780123744197

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COLEMAN, WILLIAM; TSONGALIS, GREGORY
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Book Description Academic Press, 2009. Hardback. Book Condition: NEW. 9780123744197 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE01196391

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Book Description Oxford Elsevier LTD Apr 2009, 2009. Buch. Book Condition: Neu. 279x221x36 mm. Neuware - Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ''molecular pathogenesis'' of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. Exam Master® web site will host 'Self-assessment' questions that students can use to study for the molecular section of the board exam Teaches from the perspective of 'integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease Outlines the principles and practice of molecular pathology Explains the practice of 'molecular medicine and the translational aspects of molecular pathology 640 pp. Englisch. Bookseller Inventory # 9780123744197

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Book Description Oxford Elsevier LTD Apr 2009, 2009. Buch. Book Condition: Neu. 279x221x36 mm. Neuware - Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ''molecular pathogenesis'' of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. Exam Master® web site will host 'Self-assessment' questions that students can use to study for the molecular section of the board exam Teaches from the perspective of 'integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease Outlines the principles and practice of molecular pathology Explains the practice of 'molecular medicine and the translational aspects of molecular pathology 640 pp. Englisch. Bookseller Inventory # 9780123744197

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