Three-Dimensional Electron Microscopy of Macromolecular Assemblies

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9780122650406: Three-Dimensional Electron Microscopy of Macromolecular Assemblies

Three-Dimensional Electron Microscopy of Macromolecular Assemblies is the first systematic introduction to single-particle methods of reconstruction. It covers correlation alignment, classification, 3D reconstruction, restoration, and interpretation of the resulting 3D images in macromolecular assemblies. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods.

Key Features
* Presents methods that offer an alternative to crystallographic techniques for molecules that cannot be crystallized
* Describes methods that have been instrumental in exploring the three-dimensional structure of
* the nuclear pore complex
* the calcium release channel;
* the ribosome
* chaperonins

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About the Author:

Wadsworth Center for Laboratories and Research, State of New York Department of Health, The Governor Nelson A. Rockefeller Empire State Plaza and Department of Biomedical Sciences, State University of New York at Albany, U.S.A.

Review:

"Three-Dimensional Electron Microscopy of Macromolecular Assemblies is the first systematic introduction to single-particle methods of reconstruction... The book gives an excellent review on all methodological developments in the field.. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods."
--OPTIK

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