Our understanding of human genome evolution has improved dramatically over the last decade, influenced both by technological advances and directed genome mapping programmes. This volume brings together, for the first time, data concerning the evolution of genes, multigene families and nongenic sequences in the human genome and provides a comprehensive review of this rapidly changing filed. Human Genome Evolution also considers specific areas of the genome, such as the sex chromosomes, which have been subject to unusual evolutionary forces as well as covering more general topics, including the evolution of human proteins by exon shuffling and the use of genetic polymorphisms to study human evolution.
The reviews in this volume in the Human Molecular Genetics series have been written by active researchers in key areas of human genome evolution. The book is therefore an authoritative reference source for postgraduates and researchers in human molecular genetics and evolution, and provides a valuable overview of the subject to final year undergraduates with an interest in evolution.
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Michael S. Jackson, Department of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, U.K.
Tom Strachan, Department of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, U.K.
G. Dover, Department of Genetics, University of Leicester, Leicester, UK
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