This book provides a series of comprehensive reviews from some from some of the world's leading researchers on the principles underlying gene therapeutic approaches to both inherited and acquired disease in humans. The DNA delivery systems now available to target tissue with a specific gene or oligonucleotide sequence are described in detail, and the utility of animal models as test systems is explored. In addition, Gene Therapy summarizes the results of the in vitro and in vivo clinical trials performed to date for selected disease states.
This volume in the Human Molecular Genetics series is essential reading for clinicians and research scientists who wish to be update in the principles and practice of gene therapy and its clinical applications.
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Nicholas R. Lemoine, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK
David N. Cooper, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK
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