GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease. It offers comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission. It features identification and characterization of GTPase GEFs, GAPs and effectors. It includes general methodologies to study GTPase function in vitro and in vivo.
"synopsis" may belong to another edition of this title.
Book Description Book Condition: Brand New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Bookseller Inventory # AIND-1861
Book Description Book Condition: New. New. US edition. Perfect condition. Ship by express service to USA, Canada, Australia, France, Italy, UK, Germany and Netherland. Customer satisfaction our priority. Bookseller Inventory # ABE-190516-4628
Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHAK4628
Book Description Book Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery. Bookseller Inventory # AUSBNEW-1861
Book Description Academic Press, 2005. Hardcover. Book Condition: New. 1. Bookseller Inventory # DADAX0121828093
Book Description Academic Press, 2005. Hardcover. Book Condition: New. book. Bookseller Inventory # 0121828093
Book Description Elsevier. Book Condition: New. pp. 692. Bookseller Inventory # 7370259
Book Description Book Condition: Brand New. U.S.Edition ,Brand New,Hardcover,Perfect Condition. Printed in English. excellent Quality, and customer satisfaction guaranteed. We Do not Ship APO FPO AND PO BOX. Bookseller Inventory # AORIGCB6807
Book Description Academic Press. Hardcover. Book Condition: New. 0121828093 Brand New Book in Perfect Condition.Fast Shipping with tracking number. Bookseller Inventory # PVDA-BCNPD-07049
Book Description Academic Pr, 2006. Hardcover. Book Condition: Brand New. 1st edition. 692 pages. 9.50x6.50x1.25 inches. In Stock. Bookseller Inventory # zk0121828093