"I look forward to the publication of the Handbook with great interest. There is clearly an enormous need for such a book, and I think the cell biology community--and my students--will be grateful." --
--Tim Mitchison, University of California, San Francisco"The aim of Cell Biology: A Laboratory Handbook is to assemble in one place the most important methods in cell biology, which have withstood the test of time to become classics. This goal has been admirably achieved in a three-volume set edited by Julio E. Celis. This Handbook is divided into 15 sections, starting with techniques for culturing and analyzing whole cells, progressing through sections on cell fractionation, microscopy, generation of antibodies, introduction of molecules into living cells, and ending up with methods for analysis of proteins. Chapters are short and to the point. Methods are described in sufficient detail to allow the techniques to be reproduced, and are provided as easy-to-follow recipes. Importantly, the pitfalls inherent in each technique are assembled at the end of each article. The layout is admirably clear, and the quality of the illustrations is superb. The compendium will undoubtedly prove invaluable to cell biologists and to molecular biologists who wish to study the role of macromolecules in cell function. Cell Biology: A Laboratory Handbook should become the bible of established cell biological methods." (--Tony Hunter, Salk Institute, La Jolla, California)
This Second Edition of the highly praised Cell Biology: A Laboratory Handbook brings together 260 new and revised chapters. Each chapter is concisely written and beautifully illustrated, making this attractive four-volume set a worthwhile addition to any desktop, and the up-to-date instructions for biological techniques make this reference the next best thing to having the expert at your side. Dr. Julio Celis and the Associate Editors have drawn on peer review from the scientific community to include 40 percent new material in this much-needed and updated laboratory manual. In one easy to use reference, current and classic protocols are presented in a clear and reader-friendly format that makes this manual a necessity to undergraduate and graduate students as well as technicians and instructors. -- Tony Hunter, Salk Institute, La Jolla,
A native of Chile, Dr. Julio E. Celis received his bachelor s degree from the University of Chile in 1964, and then completed his Ph.D. in the United States at the University of Iowa. After his postdoctoral training at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England, he went on to become an assistant professor at the University of Chile. Dr. Celis was named an associate professor in 1975 at Aarhus University, Denmark, and in 1987 became Chairman of the University s Institute of Medical Biochemistry. He is also the Chairman of the Danish Centre for Human Genome Research and was recently elected Secretary General-elect of the Federation of European Biochemical Societies (FEBS) 1997. With nearly 180 publications to his credit, Dr. Celis specialized areas of research include molecular mechanisms of cancer, human 2D gel protein databases and their link to genome data, signal transduction, and the biology of human skin. Married, with three children and one cat (Max William), Dr. Celis currently resides in Denmark where he holds among his many titles the chair to the Symposium and Prize Committee of the Danish Cancer Society, as well as the acting Chairman of the Nordic Molecular Biology Association (NOMBA). Dr. Celis is currently the Vice President of the European Molecular Biology Laboratory (EMBL) Council and leader of the Danish Delegation to the OECD Megascience Forum subgroup on Bioinformatics. He is also the European Union Observer to the International Nucleotide sequence database collaboration and a member of the EMBO Course Committee.