"The Handbook of Cell Signaling" is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field): Initiation: Extracellular and Membrane Events; Transmission: Effectors and Cytosolic Events; Nuclear Responses: Gene Expression and Translation; Events in Intracellular Compartments; and Cell-Cell and Cell-Matrix Interactions. Covered in extensive detail, these areas will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Tabular and well-illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. It contains approximately 470 articles, and provides well-organized sections on each essential area in signaling. It includes discussion on everything from ligand/receptor interactions to organ/organism responses.
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Ralph A. Bradshaw: University of California, San Francisco Professor of Chemistry and Pharmaceutical Chemistry and Deputy Director of the Mass Spectrometry Facility; also Professor Emeritus of the Dept of Physiology & Biophysics, UC Irvine Bradshaw is an emeritus member of the Board of Directors of the Keystone Symposia on Molecular and Cellular Biology and Co-editor of Molecular and Cellular Proteomics. His research interests are in the area of polypeptide growth factors and their receptors, cell signaling, N-terminal processing of proteins and proteomics. He has published over 300 articles in these and related areas. Edward A. Dennis: University of California, San Diego Distinguished Professor of Chemistry and Biochemistry and former Department Chair and Professor of Pharmacology in the School of Medicine, Dennis is currently Editor-in-Chief of the Journal of Lipid Research and Director of the LIPID MAPS initiative. He also served as Chair of the Board of Directors of the Keystone Symposia on Molecular and Cellular Biology and current as an Emeritus member of the Board of Directors. His current research focus is on phospholipases, cell signaling and lipidomics on which he has published over 300 papers, most related to signal transduction by lipid messengers
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