Contributions from leading authorities in the field encompass the full range of current research. Several chapters focus on the structural features of the adenylyl cyclases; their regulation by G protein subunits, both both a and bg; protein protein kinases; and calcium ions. Given balanced consideration as well are the potential physiologic roles of adenylyl cyclases.
Of special note is the presentation of a new technique -- simultaneous fluorescence radio imaging -- for studying cyclic AMP calcium kinetics in single living cells. Many believe that this innovative approach may help resolve the technical impasse that separates thinking about cAMP signaling from Ca2i signaling.
An Authoratative synthesis and review of recent major research regarding the multiple forms and multiple regulation of these elementary signaling enzymes, Adenylyl Cyclases is vital reading for all researchers directly or indirectly involved in the field.
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Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.
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Book Description Academic Press, 1998. Hardcover. Book Condition: New. 1. Bookseller Inventory # DADAX0120361329