Stem Cell Biology and Tissue Engineering in Dental Sciences - Hardcover

Ajaykumar Vishwakarma

9780123971579: Stem Cell Biology and Tissue Engineering in Dental Sciences

Hardcover

ISBN 10: 0123971578 ISBN 13: 9780123971579

Publisher: Academic Press Inc, 2014

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the importance of research in this field in the dental sciences. It compiles basic embryology and developmental biology with keen focus on stem cells, basic cell and matrix biology with relevance to tissue regeneration and repair, biomaterials (including nanotechnology) and current applications in various disciplines of dental science. Tissue engineering is an interdisciplinary field of biomedical research-which combines life, engineering, and materials sciences-to further the maintenance, repair, and replacement of diseased and damaged tissues. This emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular, and cell-based therapies for clinical application. These strategies are being developed and evaluated as potential treatments of dental conditions, particularly periodontology, endodontics, dental implantology, and oral-maxillofacial surgery. * Covers all aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization* Describes stem cell biology with details focused on dental stem cells and their potential research application throughout medicine * Describes new technologies and fabrication techniques in the fields of stem cells and biomaterial and tissue engineering research, including the latest advances in nanotechnology

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Review:

This work bridges the gap between dental science and stem cell and tissue engineering

About the Author:

Dr Ajaykumar Vishwakarma is a Post-doctoral Research Fellow with Prof. Ali Khademhosseini in the Brigham and Women's Hospital, Harvard Medical School at Harvard University, USA and also affiliated to Harvard-MIT Division of Health Sciences and Technology. He graduated from Maharashtra University of Health Science, India with a B.D.S degree and has been a recipient of the Stem Cell Training Fellowship at Centre for Cellular and Molecular Biology. He completed his MSc in Tissue Engineering and PG Certificate in Biomedical Techniques from Cardiff University, UK. Additionally, he has held key industrial positions in the past to gain experience in commercialization and translational biotechnology. His research interests include using bioengineering design principles to develop advanced therapeutic and non-therapeutic tissue engineered products for healthcare and to improve sustainability. His primary research is based on developing advanced biomaterials using micro- and nanoscale technologies to control cellular behavior and combining them with stem cells for oral and craniofacial tissue engineering. Professor Paul Sharpe is the Dickinson Professor of Craniofacial Biology at Kings College London. He graduated with a degree in biology from York University (1977) and a PhD in biochemistry from Sheffield University (1981). Following postdocs in Sheffield, Wisconsin and Cambridge he became lecturer in molecular embryology at the University of Manchester in 1987 where he established a research group working on the molecular control of tooth development. Following promotion to Reader in 1991 he was recruited to his present Chair at the Dental Institute of Guy's Hospital (later to merge with Kings College), where he established a new basic research department, the Department of Craniofacial Development and Stem Cell Biology. The department, of which he remains head, now consists of 13 academic research groups with over 80 research staff. From 2002-2008 he was Director of Research for the Dental Institute. His main research interests are the molecular control of tooth development, dental stem cell biology and tooth bioengineering. He has published over 270 research papers including articles in Nature, Science, PNAS and Cell press. He has supervised over 40 PhD students and receives funding from the MRC. He is a member of the MRC Centre for Transplantation and Biomedical Research Centre. In 2004 he was awarded the Craniofacial Biology Research Award by the International Association for Dental Research in recognition of his contribution to the understanding of how teeth develop and in 2006 his paper "Stem cell-based tissue engineering of teeth received the William J Gies award for best publication is Biomaterials and Bioengineering from the same organisation. He is on the editorial boards of several journals including J. Dent. Res. and J. Clin. Perio. Songtao Shi, D.D.S., Ph.D., is Professor at the University of Southern California Ostrow School of Dentistry. Dr. Shi received his D.D.S. degree and certificate in Pediatric Dentistry from the Peking University School of Stomatology and Ph.D. in Craniofacial Biology from the University of Southern California. Prior to joining the faculty at the University of Southern California, he served as a Principal Investigator and Clinical Fellow for nine years at the National Institute of Dental and Craniofacial Research. His research program focuses on understanding mechanism of mesenchymal stem cell (MSC)-associated diseases, developing new experimental disease models, and exploring feasibility of translating these bench discoveries to clinical therapies. His group and his collaborators were the first to identify dental pulp stem cells, baby tooth stem cells, periodontal ligament stem cells, root apical papilla stem cells, tendon stem cells, gingiva stem cells, sclera MSCs, and benign tumor MSCs

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