Linkage Thermodynamics of Macromolecular Interactions: 51 (Advances in Protein Chemistry): Volume 51 - Hardcover

9780120342518: Linkage Thermodynamics of Macromolecular Interactions: 51 (Advances in Protein Chemistry): Volume 51
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This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.

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Praise for the Volume
"The contributions are by outstanding investigators who bring both a traditional perspective on this topic and expertise and knowledge in newer aspects and applications, such as protein-nucleic acid interactions...any investigator with interests in protein folding and stability, or protein-protein or protein-ligand interaction thermodynamics or in enzyme or receptor interaction thermodynamics should find this volume useful and informative... This volume is highly recommended for protein chemists, molecular or cell biologists who need a better understanding of these topics."
--DOODY'S PUBLISHING REVIEWS (4 star rating)
Praise for the Series
"The authority, originality, and editing of the reviews are first class."
--NATURE
"The Advances in Protein Chemistry series has been a major factor in the education of protein chemists."
--JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
About the Author:
Dr. James B. Wells is a professor in the Department of Criminal Justice in the College of Justice & Safety at Eastern Kentucky University. Earlier in his career, he was a correctional officer at the Southern Ohio Correctional Facility in Lucasville, Ohio, and later, a criminal justice planner for an architectural and engineering firm that specialized in designing correctional and other justice-related facilities.

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  • PublisherAcademic Press
  • Publication date1998
  • ISBN 10 0120342510
  • ISBN 13 9780120342518
  • BindingHardcover
  • Number of pages473
  • EditorDi Cera Enrico

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